Tailor-made infrastructure for real-time investigation of prefilled syringes under varying temperature and pressure conditions using Synchrotron CT

•  Capability to measure the pre-filled syringe using Synchrotron CT

•  Temperature control of the pre-filled syringe via a liquid cooler

•  Rotary union for the cooling liquid and pressure

•  Temperature and pressure sensors for measurement and control

•  High control accuracy

•  High heat transfer from chamber to syringe

•  Pressurization via vacuum pump

•  Pressure sensor for measuring and controlling the syringe ambient pressure

•  Easy sample change

•  Sample replacement is possible without deactivating the liquid cooler

•  Temperature sensors in the pressure chamber

•  Temperature measurement directly on the glass body

•  Use of a rotary union with slip rings for cooling fluid (inlet/outlet), pressure, and 2x PT100 temperature sensors

•  Rotary union with low torque <= 0.5 Nm

•  High heat transfer to syringes via aluminum insert

•  Installation and commissioning of hardware and software

•  Controller tuning and acceptance testing in the laboratory

•  Setup of the in-situ chamber on the beamline

•  Conducting Synchrotron CT imaging experiments according to customer-specific requirements for pressure and temperature